SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®).
نویسندگان
چکیده
We describe here the development, verification and validation of the SLE-key(®) rule-out test for a definitive rule-out of a diagnosis of systemic lupus erythematosus (SLE). The test uses the proprietary iCHIP(®) micro-array technology platform (Fattal et al., 2010) to identify discriminating patterns of circulating autoantibodies among SLE patients compared with self-declared healthy individuals. Given the challenges associated with the diagnosis of SLE and the healthcare costs of delayed diagnosis and misdiagnosis, a definitive rule-out test can provide significant clinical benefits to patients and potentially major cost savings to healthcare systems.
منابع مشابه
ImmunArray Selected Peer Reviewed Publications
US Headquarters: 737 N Fifth St., Suite 304, Richmond, VA 23219 Tel: +1-804-709-0144 Fax: +1-804-709-0152 Israel Headquarters: 12 Hamada St., Entrance A – Floor 2, Rehovot, Israel, 7670315 Tel: +972-8-9365727 Fax: +972-72-2134600 1. Putterman C, Wu A, Reiner-Benaim A, Batty DS, Sanz I, Oates J, Jakobi K, Petri M, Safer P, Gerwien R, Sorek R, Blumenstein Y, Cohen IR. (2015). SLE-key® Rule-Out Se...
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ورودعنوان ژورنال:
- Journal of immunological methods
دوره 429 شماره
صفحات -
تاریخ انتشار 2016